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Publications

 

Beadle R, Frenneaux MP.  Reply: Perhexiline, Cardiac Energetics, and Heart Failure: Lessons From the First Law of Thermodynamics.  JACC Heart Failure 2015; 3(8):660.

 

Ormerod JO, Arif S, Mukadam M, Evans JD, Beadle R et al.  Short-Term Intravenous Sodium Nitrite Infusion Improves Cardiac and Pulmonary Hemodynamics in Heart Failure Patients.  Circ Heart Fail. 2015 Apr 2.

 

Beadle R, Williams L, Kuehl M et al.  Improvement in Cardiac Energetics by Perhexiline in Heart Failure due to Dilated Cardiomyopathy.  JACC Heart Fail 2015; 3:202-11.

 

Singh S, Beadle R, Cameron D et al. Randomized double-blind placebo-controlled trial of perhexiline in heart failure with preserved ejection fraction syndrome. Future Cardiol 2014; 10(6):693-698.

 

Nadir AM, Beadle R, Lim HS. Kussmaul physiology in patients with heart failure. Circ Heart Fail 2014; 7(3):440-447.

 

Beadle R, Lim HS. Pacing alternans during broad complex tachycardia. Heart Rhythm 2013 April 5.

 

Siddiqi, N., Singh, S., Beadle, R. et al Cardiac metabolism in hypertrophy and heart failure: implications for therapy. Heart Fail.Rev 2012.

 

Beadle R, Reducing the Burden of Ischemia Reperfusion : Editorial to: "Effect of Chronic CPT-1 Inhibition on Myocardial Ischemia-Reperfusion Injury (I/R) in a Model of Diet-Induced Obesity" by G. Maarman et al. Cardiovasc Drugs Ther 2012 March 14.

 

Beadle R, Williams L. An approach to echocardiography in hypertrophic cardiomyopathy and other causes of LVH. Minerva Cardioangiol 2012 January 31.

 

Williams, L, Beadle, R, and Frenneaux, M. (2011) Letter by Williams et al regarding article, "bundle-branch block morphology and other predictors of outcome after cardiac resynchronization therapy in medicare patients". Circulation, 124 (5): p. e170

 

Beadle R, Williams LK, Abozguia K et al. Metabolic manipulation in chronic heart failure: study protocol for a randomised controlled trial. Trials 2011;12:140.

                      

Beadle R, Frenneaux M. Modificiation of Myocardial Substrate Utilisation as a Therapeutic Prospect in Heart Failure. The Bulletin of the British Society of Cardiovascular Research 2011 January;24(1):4-10.

 

Beadle R, Williams L. Device therapy in hypertrophic cardiomyopathy. Expert Rev Cardiovasc Ther 2010 December;8(12):1767-75.

 

Beadle R, Williams L, Lim HS. Drug-implantable cardioverter-defibrillator interactions. Expert Rev Cardiovasc Ther 2010 September;8(9):1267-73.

 

Beadle R, Frenneaux M. Modification of myocardial substrate utilisation: a new therapeutic paradigm in cardiovascular disease. Heart 2010 June;96(11):824-30.    

 

Beadle R, Frenneaux M. Magnetic resonance spectroscopy in myocardial disease. Expert Rev Cardiovasc Ther 2010 February;8(2):269-77.

 

Lim HS, Beadle R, Frenneaux M. Death and dying in heart failure with normal ejection fraction. Am J Cardiol 2009 November 1;104(9):1311-4.

Abstracts & Presentations

 

A Nadir, R Beadle, S Lim

Kussmaul Physiology is an Independent Predictor of Adverse ClinicalOutcomes and Mortality in Patients with Heart Failure; AHA Scientific Sessions, Dallas 11/2013

 

D Monnery, R Beadle, A Patwala

The Management of Cardiac Device Infections and Incidence of Device    Infections in a Single UK Centre

EHRA Europace, Athens, June 06/2013

           

R Beadle, L Williams, M Kuehl, S Bowater, K Abozguia, K Patel, Z Yousef, F Leyva Leon, M Frenneaux

Perhexiline Corrects Energy Deficiency and Improves Symptoms in Chronic Heart Failure

European Society of Cardiology Congress, Munich 08/2012

 

Kuehl M, Beadle R, Azam M, Steeds R, Taharani A, Stevens MJ. Patients with type 2 diabetes demonstrate reduced cardiac energetics and increased LV torsion compared to healthy age matched controls.

American Diabetes Association, Philadelphia, USA 2012

 

Kuehl M, Beadle R, Muhammad A, Steeds R, Taharani A, Stevens M. Depressed cardiac energetics in patients with type 2 diabetes mellitus correlate inversely with fat content and fat mass.

DCVD EASD Study Group meeting, Munich 2011

 

R Beadle, L Williams, M Kuehl, S Bowater, K Abozguia, K Patel, Z Yousef, F Leyva Leon, M Frenneaux

Impaired Cardiac Energetic in Dilated Cardiomyopathy – Magnetic Resonance Spectroscopy at 3T

British Cardiac Society Meeting 06/2011

European Society of Cardiology Congress 08/2011

 

S Arif, B Ladak, I Rahman, R Beadle, M Frenneaux, R Bonser

Does Remote Ischaemic Pre-Conditioning Provide Second Window Endothelial Protection in Humans?

Society for Cardiothoracic Surgery Annual Meeting 04/2011

 

S Bowater, C Davies, R Beadle, S Thorne, M Frenneaux, J Marshall, P     Clift

Resting Skeletal Muscle Oxygen Consumption and Maximal Oxidative Capacity in Eisenmenger Syndrome

Medical Research Society 02/2010